Articles

Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC

Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China;Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Ludwig Institute for Cancer Research & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA;School of Pharmacy, China Medical University, Shenyang, Liaoning, China
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Division of Gynecologic Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA;Department of Pharmacology, and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine;Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, Zhejiang, China
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA;Department of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;School of Pharmacy, China Medical University, Shenyang, Liaoning, China
Department of Pediatrics, University of Cincinnati College of Medicine;Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Ludwig Institute for Cancer Research & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Department of Systems Biology & the Gehr Family Center for Leukemia Research, Beckman Research Institute of City of Hope, Monrovia, CA, USA;Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA
Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China;Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, China
Vol. 105 No. 1 (2020): January, 2020 https://doi.org/10.3324/haematol.2018.208835